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CIE A Level Biology復(fù)習(xí)筆記12.2.5 Aerobic Respiration: The Krebs Cycle

Category: A-level課程, 教材筆記, 福利干貨 Date: 2022年8月10日下午5:44

Aerobic Respiration: Outline of the Krebs Cycle

The Krebs cycle (sometimes called the citric acid cycle) consists of a?series of enzyme-controlled reactions
Acetyl CoA (2C) enters?the circular pathway via the?link reaction
4 carbon (4C) oxaloacetate accepts the 2C acetyl fragment from acetyl CoA to form citrate (6C)
Citrate is then converted back to oxaloacetate?through a series of small reactions

Regeneration-of-Oxaloacetate

The regeneration of oxaloacetate

Aerobic Respiration: The Krebs Cycle

The steps in the Krebs cycle

Oxaloacetate is regenerated?in the Krebs cycle through a series of reactions
Decarboxylation of citrate
- Releasing?2 CO₂?as waste gas
Dehydrogenation of citrate
- Releasing H atoms that reduce coenzymes NAD and FAD
- 8H + 3NAD + FAD →?3NADH + 3H⁺?+ FADH₂
Substrate-level phosphorylation
- A phosphate is transferred from one of the intermediates to ADP, forming?1 ATP

The-Krebs-Cycle_1

The Krebs cycle

Exam Tip

It is a good idea to learn the Krebs cycle in detail. You may be asked to name the important molecules in the Krebs cycle like oxaloacetate. It is also worth noting how the?number of carbon atoms?in the substrate molecule changes as the cycle progresses.

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