2018英特爾ISEF獲獎作品摘要 生物醫(yī)學(xué)工程 Intel Finalist Abstract Biomedical Engineering

獲獎作品基本信息

年份	2018
學(xué)科	生物醫(yī)學(xué)工程 Biomedical Engineering
國家/州	United States of America

獲獎作品名稱

A Fully Functional Closed- Loop System Using Ultrasound Imaging to Automatically Detect Lipohypertrophy in People with Insulin-Dependent Diabetes

獲獎作品摘要

Insulin Dependent Diabetes is a chronic condition that affects over 200 million people worldwide. Diabetic patients keep this disease under control by externally administrating Insulin hormone through multiple daily injections (MDI) or through insulin pumps. One of the key challenges of MDI is the buildup of adipose tissue under the skin, known as Lipohypertrophy. This causes blunted insulin absorption in the subcutaneous fat layer, leading to poor management of diabetes. Lipohypertrophy goes largely undetected since it is not visible to naked eye and hard to detect until the condition gets really severe and painful.? Many diabetics have no idea of these fat regions and continue to administer MDI into these low insulin absorption areas leading to further aggravation of the condition. The purpose of this project is to create a fully functional closed loop system that is able to determine Lipohypertrophic regions using ultrasound technology. Utilizing optimized edge detection algorithms the system can detect the existence of fat-buildup and pinpoint the locations affected by Lipohypertrophy. The closed-loop system was tested in three phases; The initial phase tested the algorithm on published Lipohypertrophic Images obtained from the Profil Institute for Metabolic Research in Germany. The algorithm was able to detect these regions with more than 85% accuracy.? The next phases, involved human patients, tested the applicability of this algorithm in real life scenarios. The system was able to properly detect Lipohypertrophy. In conclusion, the fully functional closed loop system uses advanced imaging techniques to automatically detect Lipohypertrophy allowing for determination of optimal injection locations and therby reducing diabetic-related complication

 

 

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ISEF 簡介

英特爾國際科學(xué)與工程大獎賽，簡稱 "ISEF"，由美國 Society for Science and the Public（科學(xué)和公共服務(wù)協(xié)會）主辦，英特爾公司冠名贊助，是全球規(guī)模最大、等級最高的中學(xué)生的科研科創(chuàng)賽事。ISEF 的學(xué)術(shù)活動學(xué)科包括了所有數(shù)學(xué)、自然科學(xué)、工程的全部領(lǐng)域和部分社會科學(xué)。ISEF 素有全球青少年科學(xué)學(xué)術(shù)活動的“世界杯”之美譽(yù)，旨在鼓勵學(xué)生團(tuán)隊協(xié)作，開拓創(chuàng)新，長期專一深入地研究自己感興趣的課題。

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英特爾 ISEF 學(xué)術(shù)活動詳細(xì)介紹

英特爾 ISEF 全程指導(dǎo)方案

· 數(shù)學(xué) · 物理 · 化學(xué) · 生物 · 計算機(jī) · 工程 ·

學(xué)科簡介：生物醫(yī)學(xué)工程 Biomedical Engineering

Projects that involve the application of engineering principles and design concepts to medicine and biology for healthcare purposes including diagnosis, monitoring and therapy. ?Prominent biomedical engineering applications include the development of biocompatible prostheses, various diagnostic and therapeutic medical devices ranging from clinical equipment to micro-implants, common imaging equipment such as MRIs and EEGs, regenerative tissue growth, pharmaceutical drugs and therapeutic biologicals.

Subcategories:

Biomaterials and Regenerative Medicine?(BMR):?These studies involve the creation or use of biomaterials or biocompatible materials to construct a whole or a part of a living structure. These studies can include scaffolds for recruiting or supporting regenerative cells or tissues or the engineering designs for creating the correct environment for regenerative growth.

Biomechanics?(BIE):?Studies that apply classical mechanics (statics, dynamics, fluids, solids, thermodynamics, and continuum mechanics) to understand the function of biological tissues, organs, and systems and solve biological or medical problems. It includes the study of motion, material deformation, flow within the body and in devices, and transport of chemical constituents across biological and synthetic media and membranes.

Biomedical Devices (BDV):?The study and/or construction of an apparatus that use electronics and other measurement techniques to diagnose, prevent and/or treat diseases or other conditions within or on the body.

Biomedical Imaging?(IMG):?The study and/or construction of an apparatus or technique that combines knowledge of a unique physical phenomenon (sound, radiation, magnetism, etc) with high speed electronic data processing, analysis and display to generate an image to support biomedical advances and procedures.

Cell and Tissue Engineering?(CTE):?Studies that utilize the anatomy, biochemistry and mechanics of cellular and sub-cellular structures in order to understand disease processes and to be able to intervene at very specific sites.

Synthetic Biology (SYN):?Studies that involve the design and construction of new biological parts, devices and systems. Such studies include biological circuit design, genetic circuits, protein engineering, nucleic acid engineering, rational design, directed evolution and metabolic engineering.

OTH?Other?(OTH):?Studies that cannot be assigned to one of the above subcategories. If the project involves multiple subcategories, the principal subcategory should be chosen instead of Other.