2018英特爾ISEF獲獎作品摘要 行為與社會科學 Intel Finalist Abstract Behavioral and Social Sciences

獲獎作品基本信息

年份	2018
學科	行為與社會科學 Behavioral and Social Sciences
國家/州	United State of America

獲獎作品名稱

The Effect of Metformin on Post Traumatic Brain Injury Learning and Learning Disabilities

獲獎作品摘要

Traumatic brain injuries (TBIs) whether mild, moderate or severe, can have a direct and definite impact on a person’s everyday life. The initial treatment after TBI usually consists of interventions to train individuals to learn new knowledge and skills or new ways to access previously acquired knowledge and skills. Other treatments, like Deep Brain Stimulation which

works to stimulate the nerves around the lesion (injured) area, are highly invasive. Metformin, a drug??used for type 2 diabetes patients, has shown to promote neurogenesis in mice. ??This increase could potentially reverse the effects of a TBI by creating new nervous tissue to repair the lesion area.

This study used the??Drosophila melanogaster model, due to their fast-reproductive cycle and their similar nervous system to that of a human. ??Through the use of a T-maze the learning abilities of flies was tested as well as the effect of Metformin in different doses. ??Before testing flies were trained to associate a sucrose reward with an odor and no reward and another, then both were presented in the T-maze. ??It was found, using a One-way ANOVA test and a Tukey test, that 3.5 Add to dictionary of Metformin significantly increased learning in the flies given a TBI (p<.o5)

 

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ISEF 簡介

英特爾國際科學與工程大獎賽，簡稱 "ISEF"，由美國 Society for Science and the Public（科學和公共服務協(xié)會）主辦，英特爾公司冠名贊助，是全球規(guī)模最大、等級最高的中學生的科研科創(chuàng)賽事。ISEF 的學術活動學科包括了所有數(shù)學、自然科學、工程的全部領域和部分社會科學。ISEF 素有全球青少年科學學術活動的“世界杯”之美譽，旨在鼓勵學生團隊協(xié)作，開拓創(chuàng)新，長期專一深入地研究自己感興趣的課題。

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英特爾 ISEF 學術活動詳細介紹

英特爾 ISEF 全程指導方案

· 數(shù)學 · 物理 · 化學 · 生物 · 計算機 · 工程 ·

學科簡介：行為與社會科學 Behavioral and Social Sciences

The science or study of the thought processes and behavior of humans and other animals in their interactions with the environment studied through observational and experimental methods.

Subcategories:

Clinical and Developmental Psychology (CLN):?The study and treatment of emotional or behavioral disorders. Developmental psychology is concerned with the study of progressive behavioral changes in an individual from birth until death.

Cognitive Psychology?(COG):?The study of cognition, the mental processes that underlie behavior, including thinking, deciding, reasoning, and to some extent motivation and emotion.

Neuroscience (NEU):?Studies of the neural basis of cognitive processes, including learning and memory, language and thought, perception, attention, and affect. It investigates the human brain, from the functional organization of large scale cerebral systems to microscopic neurochemical processes.

Physiological Psychology?(PHY):?The study of the biological and physiological basis of behavior. This field studies the neural mechanisms of perception and behavior through direct manipulation of the brain in controlled experiments.

Sociology and Social Psychology?(SOC):?The study of human social behavior, especially the study of the origins, organization, institutions, and development of human society. Sociology is concerned with all group activities-economic, social, political, and religious.

Other?(OTH):?Studies that cannot be assigned to one of the above subcategories. If the project involves multiple subcategories, the principal subcategory should be chosen instead of Other.