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2015 AP Biology Practice Exam Multiple Choice and Grid-In Questions Free Download

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1）A genetic counselor is consulted by a young man who is worried about developing Huntington’s disease, an inherited disorder caused by a dominant allele of a single gene. The young man explains that his cousin was recently diagnosed with Huntington’s disease, and the news has caused him to consider his own risk of developing the disorder. Which of the following questions will best help the genetic counselor to evaluate the risk of the young man developing Huntington’s disease and transmitting it to his children?

1. Were you and your cousin born in the same geographical area?
2. Were your parents or grandparents ever diagnosed with Huntington’s disease?
3. Were you in physical contact with a person diagnosed with Huntington’s disease?
4. Were you ever exposed to substances that are suspected of being mutagens?

2)Over several years, bacteria were isolated from members of a human population and tested for antibiotic resistance. The percent of bacterial isolates that were found to be antibiotic resistant is presented in the graph above for each year of the study. Which of the following conclusions is best supported by the information presented in the graph?

1. The greatest increase in antibiotic resistance occurred from the first year to the third year of the study.
2. Gene flow in the population occurred at the same rate for the entire duration of the eight-year study.
3. Because evolution in bacterial populations occurs over millions of years, the results are due to random variation.
4. Natural selection over multiple generations is favoring antibiotic resistance in the population of bacteria.

3)Lobe-finned fishes were present in the oceans of the world approximately 400 million years ago. The first tetrapods (vertebrates that had limbs and could move on land) date to about 365 million years ago. One hypothesis states that early tetrapods evolved from lobe-finned fishes. Which of the following is the best plan for testing the hypothesis?

1. Determining the number of fins found on lobe-finned fishes from different geographical locations
2. Measuring the proportion of radioisotopes found in fossils of early tetrapods
3. Comparing the arrangements of bones in the fins of lobe-finned fishes and limbs of the earliest tetrapods
4. Sequencing DNA isolated from fossils of lobe-finned fishes to determine the size of the genome

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